Reviews
Short-Course Regimen for MDR-TB
4 Feb 2020
Short-Course Regimen for Multidrug-Resistant Tuberculosis: A Decade of Evidence
Molecular MDR diagnosis
8 May 2019
Molecular Diagnosis of Drug-Resistant Tuberculosis; A Literature Review
Front Microbiol. 2019; 10: 794.
TB and its Treatment
16 Apr 2019
Tuberculosis and its Treatment: An Overview.
Mini Rev Med Chem. 2018;18(1):58-71
Controversies about MDR and XDR-TB treatment
16 Apr 2019
Recent controversies about MDR and XDR-TB: Global implementation of the WHO shorter MDR-TB regimen and bedaquiline for all with MDR-TB?
Respirology. 2018 Jan;23(1):36-45
New treatment of TB
16 Apr 2019
New drugs and perspectives for new anti-tuberculosis regimens.
Pulmonology. 2018 Mar - Apr;24(2):86-98
TB in South Asia
16 Apr 2019
Tuberculosis in South Asia: a tide in the affairs of men.
Multidiscip Respir Med. 2018 Mar 22;13:10
TB in older people
16 Apr 2019
Epidemiological, clinical and mechanistic perspectives of tuberculosis in older people.
Respirology. 2018 Jun;23(6):567-575
Cost of TB in patients with HIV
16 Apr 2019
Cost of Tuberculosis Diagnosis and Treatment in Patients with HIV: A Systematic Literature Review.
Value Health. 2018 Apr;21(4):482-490
RpoB mutations associated with Rifampicin-resistance in Mtb
16 Apr 2019
Mutations inside rifampicin-resistance determining region of rpoB gene associated with rifampicin-resistance in Mycobacterium tuberculosis.
J Infect Public Health. 2018 Sep - Oct;11(5):605-610
TB elimination
16 Apr 2019
Tuberculosis elimination: where are we now?
Eur Respir Rev. 2018 Jun 13;27(148)
Host Directed Therapies for Tuberculosis
16 Apr 2019
Host Directed Therapies for Tuberculosis: Futures Strategies for an Ancient Disease.
Chemotherapy. 2018;63(3):172-180
Microbiome and TB
16 Apr 2019
The Microbiome and Tuberculosis: Early Evidence for Cross Talk.
Drug discovery
16 Apr 2019
Translational Potential of Therapeutics Targeting Regulatory Myeloid Cells in Tuberculosis.
Front Cell Infect Microbiol. 2018 Sep 21;8:332
Treatment of drug-resistant TB
16 Apr 2019
New and repurposed drugs to treat multidrug- and extensively drug-resistant tuberculosis.
J Bras Pneumol. 2018 Apr;44(2):153-160
Consensus numbering for rpoB gene mutations
16 Apr 2019
Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
Clin Microbiol Infect. 2017 Mar;23(3):167-172
Management of patients with MDR and XDR-TB
16 Apr 2019
Clinical management of adults and children with multidrug-resistant and extensively drug-resistant tuberculosis.
Clin Microbiol Infect. 2017 Mar;23(3):131-140
WGS
16 Apr 2019
Mycobacterium tuberculosis and whole genome sequencing: a practical guide and online tools available for the clinical microbiologist.
Clin Microbiol Infect. 2017 Feb;23(2):69-72.
MDR-TB and migration to Europe
16 Apr 2019
Multidrug-resistant tuberculosis and migration to Europe.
Clin Microbiol Infect. 2017 Mar;23(3):141-146
Drug resistance testing
16 Apr 2019
Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives.
Clin Microbiol Infect. 2017 Mar;23(3):154-160
Targets for TB therapy
16 Apr 2019
DNA topoisomerase I and DNA gyrase as targets for TB therapy.
Drug Discov Today. 2017 Mar;22(3):510-518
DOTS-Plus
16 Apr 2019
Treatment outcomes for multidrug-resistant tuberculosis under DOTS-Plus: a systematic review and meta-analysis of published studies.
Infect Dis Poverty. 2017 Jan 17;6(1):7
Line probe assays
16 Apr 2019
Accuracy of line probe assays for the diagnosis of pulmonary and multidrug-resistant tuberculosis: a systematic review and meta-analysis.
Eur Respir J. 2017 Jan 18;49(1)
Risk of epidemic with MDR strains
16 Apr 2019
The risk of global epidemic replacement with drug-resistant Mycobacterium tuberculosis strains.
Int J Infect Dis. 2017 Mar;56:14-20
Isolation of Patients
14 Apr 2019
De-isolation of patients with pulmonary tuberculosis after start of treatment - clear, unequivocal guidelines are missing.
Int J Infect Dis. 2017 Mar;56:34-38
Delamanid and Bedaquiline
14 Apr 2019
Combined Use of Delamanid and Bedaquiline to Treat Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: A Systematic Review.
Int J Mol Sci. 2017 Feb 7;18(2)
Isoniazid-resistant TB
14 Apr 2019
Isoniazid-resistant tuberculosis: a cause for concern?
Int J Tuberc Lung Dis. 2017 Feb 1;21(2):129-139
Dormancy and Host Responses
14 Apr 2019
Mycobacterial Dormancy Systems and Host Responses in Tuberculosis.
Front Immunol. 2017 Feb 15;8:84
Combination Therapy for Tuberculosis
14 Apr 2019
Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application.
Treatment of MDR TB
14 Apr 2019
An updated systematic review and meta-analysis for treatment of multidrug-resistant tuberculosis.
Eur Respir J. 2017 Mar 22;49(3)
MmpL transporters
14 Apr 2019
The diverse family of MmpL transporters in mycobacteria: from regulation to antimicrobial developments.
Mol Microbiol. 2017 Jun;104(6):889-904
Treatment of LTBI
14 Apr 2019
Efficacy and completion rates of rifapentine and isoniazid (3HP) compared to other treatment regimens for latent tuberculosis infection: a systematic review with network meta-analyses.
BMC Infect Dis. 2017 Apr 11;17(1):265
Drug Discovery
14 Apr 2019
Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery.
Drug resistance
14 Apr 2019
New Insights in to the Intrinsic and Acquired Drug Resistance Mechanisms in Mycobacteria.
Front Microbiol. 2017 Apr 25;8:681.
Latent tuberculosis infection & TB elimination
14 Apr 2019
Latent tuberculosis infection: the final frontier of tuberculosis elimination in the USA.
Lancet Infect Dis. 2017 Oct;17(10):e327-e333
Drug discovery
14 Apr 2019
Antimycobacterial Metabolism: Illuminating Mycobacterium tuberculosis Biology and Drug Discovery.
Trends Microbiol. 2017 Sep;25(9):756-767
Heterogeneity
13 Apr 2019
Heterogeneity in tuberculosis.
Nat Rev Immunol. 2017 Nov;17(11):691-702
Moxifloxacin
13 Apr 2019
A Review of Moxifloxacin for the Treatment of Drug-Susceptible Tuberculosis.
J Clin Pharmacol. 2017 Nov;57(11):1369-1386
Dormancy
13 Apr 2019
Fighting tuberculosis by drugs targeting nonreplicating Mycobacterium tuberculosis bacilli.
Int J Mycobacteriol. 2017 Jul-Sep;6(3):213-221
Child contact management
13 Apr 2019
Child contact management in high tuberculosis burden countries: A mixed-methods systematic review.
PLoS One. 2017 Aug 1;12(8):e0182185.
Treatment of MDR TB in children
13 Apr 2019
Current therapies for the treatment of multidrug-resistant tuberculosis in children in India.
Expert Opin Pharmacother. 2017 Oct;18(15):1595-1606
Prevention in HIV-infected children
13 Apr 2019
Isoniazid for preventing tuberculosis in HIV-infected children.
Cochrane Database Syst Rev. 2017 Aug 29;8:CD006418
TB control
13 Apr 2019
Implementation strategies for health systems in low-income countries: an overview of systematic reviews.
Cochrane Database Syst Rev. 2017 Sep 12;9:CD011086
Biomarkers
13 Apr 2019
Mycobacteria-derived biomarkers for tuberculosis diagnosis. Druszczynska M, Wawrocki S, Szewczyk R, Rudnicka W.
Indian J Med Res. 2017 Dec;146(6):700-707
Meningitis
13 Apr 2019
Tuberculous Meningitis in Children and Adults: New Insights for an Ancient Foe. Mezochow A, Thakur K, Vinnard C.
Curr Neurol Neurosci Rep. 2017 Sep 20;17(11):85
Diabetes and TB
9 Apr 2019
The global dynamics of diabetes and tuberculosis: the impact of migration and policy implications. Girardi E, Sañé Schepisi M, Goletti D, Bates M, Mwaba P, Yeboah-Manu D, Ntoumi F, Palmieri F, Maeurer M, Zumla A, Ippolito G.
HIV and TB
9 Apr 2019
Integrated therapy for HIV and tuberculosis. Manosuthi W, Wiboonchutikul S, Sungkanuparph S.
Immigrants population and TB treatment
9 Apr 2019
Systematic review of risk factors for nonadherence to TB treatment in immigrant populations. Lin S, Melendez-Torres GJ.
Regimens for isoniazid-resistant tuberculosis
9 Apr 2019
What are the most efficacious treatment regimens for isoniazid-resistant tuberculosis? A systematic review and network meta-analysis. Stagg HR, Harris RJ, Hatherell HA, Obach D, Zhao H, Tsuchiya N, Kranzer K, Nikolayevskyy V, Kim J, Lipman MC, Abubakar I.
Xpert MTB/RIF
9 Apr 2019
Development, roll-out and impact of Xpert MTB/RIF for tuberculosis: what lessons have we learnt and how can we do better? Albert H, Nathavitharana RR, Isaacs C, Pai M, Denkinger CM, Boehme CC.
Incarceration and TB transmission
9 Apr 2019
The perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia. Altice FL, Azbel L, Stone J, Brooks-Pollock E, Smyrnov P, Dvoriak S, Taxman FS, El-Bassel N, Martin NK, Booth R, Stöver H, Dolan K, Vickerman P.
Microbiome
9 Apr 2019
Microbiome Changes during Tuberculosis and Antituberculous Therapy. Hong BY, Maulén NP, Adami AJ, Granados H, Balcells ME, Cervantes J.
Management of HIV-associated pulmonary tuberculosis
9 Apr 2019
Current trends and intricacies in the management of HIV-associated pulmonary tuberculosis. Gopalan N, Chandrasekaran P, Swaminathan S, Tripathy S.
Autophagy
9 Apr 2019
Bacterial Pathogens versus Autophagy: Implications for Therapeutic Interventions. Kimmey JM, Stallings CL.
Translational Research for Tuberculosis Elimination
9 Apr 2019
Translational Research for Tuberculosis Elimination: Priorities, Challenges, and Actions. Lienhardt C, Lönnroth K, Menzies D, Balasegaram M, Chakaya J, Cobelens F, Cohn J, Denkinger CM, Evans TG, Källenius G, Kaplan G, Kumar AM, Matthiessen L, Mgone CS, Mizrahi V, Mukadi YD, Nguyen VN, Nordström A, Sizemore CF, Spigelman M, Squire SB, Swaminathan S, Van Helden PD, Zumla A, Weyer K, Weil D, Raviglione M.
Next-Generation Whole Genome Sequencing
30 Jan 2019
Mycobacterium tuberculosis Next-Generation Whole Genome Sequencing: Opportunities and Challenges. Iketleng T, Lessells R, Dlamini MT, Mogashoa T, Mupfumi L, Moyo S, Gaseitsiwe S, de Oliveira T. Tuberc Res Treat. 2018 Dec 9;2018:1298542
Human genetics of mycobacterial disease.
4 Jan 2019
Human genetics of mycobacterial disease. Dallmann-Sauer M, Correa-Macedo W, Schurr E. Mamm Genome. 2018 Aug;29(7-8):523-538.
Alveolar Macrophages
4 Jan 2019
Alveolar Macrophages in the Resolution of Inflammation, Tissue Repair, and Tolerance to Infection. Allard B, Panariti A, Martin JG. Front Immunol. 2018 Jul 31;9:1777.
Tuberculosis in European Regions
4 Jan 2019
What Constitutes an Effective and Efficient Package of Services for the Prevention, Diagnosis, Treatment and Care of Tuberculosis among Refugees and Migrants in the WHO European Region? Themed Issues on Migration and Health, VIII [Internet]. Hargreaves S, Rustage K, Nellums LB, Powis J, Milburn J, Severoni S, Dara M, Puthoopparambil SJ, Friedland JS. Copenhagen: WHO Regional Office for Europe; 2018.
HIV and Tuberculosis
4 Jan 2019
High HIV and active tuberculosis prevalence and increased mortality risk in adults with symptoms of TB: a systematic review and meta-analyses. Nliwasa M, MacPherson P, Gupta-Wright A, Mwapasa M, Horton K, Odland JØ, Flach C, Corbett EL. J Int AIDS Soc. 2018 Jul;21(7):e25162.
BCG Complications
4 Jan 2019
Bacille Calmette-Guerin Complications in Newly Described Primary Immunodeficiency Diseases: 2010-2017. Nunes-Santos CJ, Rosenzweig SD. Front Immunol. 2018 Jun 22;9:1423.
Molecular genetic tools
4 Jan 2019
Advances in the development of molecular genetic tools for Mycobacterium tuberculosis. Chhotaray C, Tan Y, Mugweru J, Islam MM, Adnan Hameed HM, Wang S, Lu Z, Wang C, Li X, Tan S, Liu J, Zhang T. J Genet Genomics. 2018 Jun 18. pii: S1673-8527(18)30114-0.
Linezolid
4 Jan 2019
Linezolid: a review of its properties, function, and use in critical care. Hashemian SMR, Farhadi T, Ganjparvar M. Drug Des Devel Ther. 2018 Jun 18;12:1759-1767.
Drug-resistant tuberculosis: diagnosis and treatment.
4 Jan 2019
Drug-resistant tuberculosis: challenges and opportunities for diagnosis and treatment. Koch A, Cox H, Mizrahi V. Curr Opin Pharmacol. 2018 Jun 6;42:7-15.
Delamanid: From discovery to its use...
8 Sep 2018
Delamanid: From discovery to its use for pulmonary multidrug-resistant tuberculosis (MDR-TB). Tuberculosis, Volume 111, 2018, pp. 20-30. Yongge Liu, Makoto Matsumoto, Hidekaza Ishida, Kinue Ohguro, Masuhiro Yoshitake, Rajesh Gupta, Lawrence Geiter, Jeffrey Hafkin.
Rapid molecular assays for detection of tuberculosis.
8 Sep 2018
Rapid molecular assays for detection of tuberculosis. Eddabra R, Ait Benhassou H. Pneumonia (Nathan). 2018 May 25;10:4.
Autophagy and Its Interaction...
8 Sep 2018
Autophagy and Its Interaction With Intracellular Bacterial Pathogens. Siqueira MDS, Ribeiro RM, Travassos LH. Front Immunol. 2018 May 23;9:935.
Mycobacterium tuberculosis: An Adaptable Pathogen...
8 Sep 2018
Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human Diseases. Chai Q, Zhang Y, Liu CH. Front Cell Infect Microbiol. 2018 May 15;8:158.
Molecular Targets Related Drug Resistance Mechanisms...
8 Sep 2018
Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains. Hameed HMA, Islam MM, Chhotaray C, Wang C, Liu Y, Tan Y, Li X, Tan S, Delorme V, Yew WW, Liu J, Zhang T. Front Cell Infect Microbiol. 2018 Apr 10;8:114.
New Players in Immunity to Tuberculosis...
8 Sep 2018
New Players in Immunity to Tuberculosis: The Host Microbiome, Lung Epithelium, and Innate Immune Cells. Gupta N, Kumar R, Agrawal B. Front Immunol. 2018 Apr 10;9:709.